<p>The present invention relates to an insulin analog in which insulin titer is reduced compared with a natural form and the binding force to an insulin receptor is reduced in order to increase the half-life of insulin in the blood; a conjugate in which the insulin analog and a carrier are connected; an extended release preparation containing the conjugate; and a method for preparing the conjugate.</p>
申请公布号
KR20140106452(A)
申请公布日期
2014.09.03
申请号
KR20140022909
申请日期
2014.02.26
申请人
HANMI PHARM. CO., LTD.
发明人
KWON, SE CHANG;KIM, DAE JIN;KIM, SEUNG SU;KIM, JIN YOUNG;KIM, HYUN UK;JANG, MYUNG HYUN;JUNG, SUNG YOUB;CHOI, IN YOUNG;HUH, YONG HO;HONG, SUNG HEE;HWANG, SANG YOUN