摘要 |
The present invention relates to a composition for inhibiting cellular senescence which includes juglanin as an active ingredient. The present invention provides the composition for inhibiting cellular senescence which inhibits senescence or replicative senescence of fibroblast which are induced by adriamycin. Specifically, the juglanin is isolated from Polygoniavicularisherba extract. By inhibiting cellular senescence of human fibroblast, the composition for inhibiting cellular senescence which includes juglanin as an active ingredient can be used for senescence related diseases such as skin aging, rheumatoid arthritis, degenerative arthritis, hepatitis, chronic skin damage tissue, artery hardening, benign prostatic hyperplasia, liver cancer and the likes. |