发明名称 |
A METHOD OF TREATING MUCUS HYPERSECRETION |
摘要 |
<p>The present invention relates generally to a method of reducing unwanted airway tissue mucus secretion in a mammal and to agents useful for same. More particularly, the present invention relates to a method of reducing airway tissue mucus hypersecretion in a mammal by downregulating the functional level of activin or upregulating the functional level of follistatin. The method of the present invention is useful, inter alia, in the treatment and/or prophylaxis of conditions characterised by airway tissue mucus dysfunction, such as overproduction of mucus or decreased mucus clearance, and where a reduction in mucus secretion levels would thereby alleviate the condition.</p> |
申请公布号 |
EP2771017(A1) |
申请公布日期 |
2014.09.03 |
申请号 |
EP20120843939 |
申请日期 |
2012.10.26 |
申请人 |
PARANTA BIOSCIENCES LIMITED |
发明人 |
O'HEHIR, ROBYN;HARDY, CHARLES;DE KRETSER, DAVID |
分类号 |
A61K31/711;A61K31/7105;A61K38/00;A61K39/395;A61P11/00;A61P11/06;A61P11/12;A61P43/00 |
主分类号 |
A61K31/711 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|