发明名称 |
METHODS AND COMPOSITIONS FOR ASSESSING PATIENTS WITH REPRODUCTIVE FAILURE USING IMMUNE CELL-DERIVED MICRORNA |
摘要 |
The invention is directed to methods and compositions for collecting immune cells, preferably peripheral blood mononuclear cells (PBMCs), before or after an intervention, extracting microRNA-comprising RNA from said cells, quantifying microRNAs within the extracted RNA, determining one or more microRNAs that display a bimodal response amongst a statistically sufficient number of patient samples. Patients are then preferably segregated into groups according to their response. |
申请公布号 |
EP2771490(A1) |
申请公布日期 |
2014.09.03 |
申请号 |
EP20120844262 |
申请日期 |
2012.10.25 |
申请人 |
WINGER, EDWARD E.;REED, JANE L. |
发明人 |
WINGER, EDWARD E.;REED, JANE L. |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|