Systems and methods for replacing signal artifacts in a glucose sensor data stream

摘要

Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.

主权项

1. A method for processing data from a glucose sensor, comprising:
monitoring a data stream from a glucose sensor; detecting transient non-glucose related signal artifacts in the data stream and evaluating a severity, wherein evaluating a severity comprises evaluating whether the one or more first estimated glucose values is outside a predetermined range, wherein the predetermined range is defined by boundaries derived from a projected rate of change and/or acceleration of the one or more first estimated glucose values; and replacing with an electronic device at least some of the signal artifacts with one or more second estimated glucose values in response to the evaluated severity meeting a criterion.