System and method for decompensation detection and treatment based on patient hemodynamics

摘要

A system and method for detecting and treating symptoms of early decompensation utilizing a cardiac rhythm management. The system applies an electrical stimulus to the patient's heart at a first set of pacing parameters including a lower rate limit (LRL) setting, and acquires a coronary venous pressure (CVP) signal from a pressure sensor implanted in a coronary vein of the patient. An average coronary venous end diastolic pressure (CV-EDP) value is calculated from the CVP signal. The system monitors the average CV-EDP value over a predetermined interval, and dynamically adjusts the LRL setting responsive to the detection of a first or a second predetermined event based on the average CV-EDP value.

主权项

1. A method of operating an implanted cardiac rhythm management system in a patient, the method comprising:
applying an electrical stimulus to the patient's heart at a first set of pacing parameters including a lower rate limit (LRL) setting; acquiring a coronary venous pressure (CVP) signal from a pressure sensor implanted in a coronary vein of the patient; calculating an average coronary venous end diastolic pressure (CV-EDP) value from the CVP signal; monitoring the average CV-EDP value, such monitoring including detecting an increase in the average CV-EDP value above a threshold indicative of decompensation and subsequently detecting a reduction in the average CV-EDP value below the threshold indicative of termination of the decompensation; and dynamically adjusting the LRL setting based on the average CV-EDP value by increasing the LRL setting in response to detecting the increase in the average CV-EDP value above the threshold and reducing the LRL setting in response to detecting the reduction in the average CV-EDP value below the threshold.