发明名称 |
Antitumor agent |
摘要 |
An antitumor agent containing, in combination, at least one kind of antitumor agent selected from the group consisting of an antitumor agent that forms a cross-link with DNA and shows an antitumor effect, an antimetabolite antitumor agent and a taxane antitumor agent, and a histone deacetylase inhibitor. According to the present invention, an antitumor agent causing reduced side effects and having a superior antitumor activity can be provided. |
申请公布号 |
US8822422(B2) |
申请公布日期 |
2014.09.02 |
申请号 |
US201113046082 |
申请日期 |
2011.03.11 |
申请人 |
Astellas Pharma Inc. |
发明人 |
Naoe Yoshinori;Inoue Takeshi;Kano Yasuhiko |
分类号 |
A61K38/12;A61P35/00;C07K7/50;A61K31/122;A61K45/06;A61K31/337 |
主分类号 |
A61K38/12 |
代理机构 |
Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P. |
代理人 |
Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P. |
主权项 |
1. A method for chemotherapy of a tumor consisting of administering a compound of formula (I) and paclitaxel to a subject having prostate cancer;
wherein the compound of formula (I) is: or a pharmaceutically acceptable salt thereof. |
地址 |
Tokyo JP |