发明名称 Antitumor agent
摘要 An antitumor agent containing, in combination, at least one kind of antitumor agent selected from the group consisting of an antitumor agent that forms a cross-link with DNA and shows an antitumor effect, an antimetabolite antitumor agent and a taxane antitumor agent, and a histone deacetylase inhibitor. According to the present invention, an antitumor agent causing reduced side effects and having a superior antitumor activity can be provided.
申请公布号 US8822422(B2) 申请公布日期 2014.09.02
申请号 US201113046082 申请日期 2011.03.11
申请人 Astellas Pharma Inc. 发明人 Naoe Yoshinori;Inoue Takeshi;Kano Yasuhiko
分类号 A61K38/12;A61P35/00;C07K7/50;A61K31/122;A61K45/06;A61K31/337 主分类号 A61K38/12
代理机构 Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P. 代理人 Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
主权项 1. A method for chemotherapy of a tumor consisting of administering a compound of formula (I) and paclitaxel to a subject having prostate cancer; wherein the compound of formula (I) is: or a pharmaceutically acceptable salt thereof.
地址 Tokyo JP