Method and apparatus for cardiac arrhythmia classification using sample entropy

摘要

An implantable medical device includes an arrhythmia detection and classification system that classifies an arrhythmia episode based on an irregularity parameter and/or a complexity parameter. The arrhythmia episode is detected from a cardiac signal. The irregularity parameter is indicative of the degree of cycle length irregularity of the cardiac signal and the complexity parameter is indicative of the degree of morphological complexity of the cardiac signal. One example of the irregularity parameter is an irregularity sample entropy, or a parameter related to the irregularity sample entropy, computed to indicate the cycle length irregularity. One example of the complexity parameter is a complexity sample entropy, or a parameter related to the complexity sample entropy, computed to indicate the morphological complexity. In one embodiment, the detected arrhythmia episode is classified using both the irregularity parameter and the complexity parameter.

主权项

1. A system for classifying cardiac arrhythmias, the system comprising:
a signal input to receive a cardiac signal indicative of a detected arrhythmia episode; an irregularity analyzer and a complexity analyzer, coupled to the signal input, the irregularity analyzer including an irregularity entropy computer adapted to compute an irregularity parameter ΓI indicative of a degree of cycle length irregularity of the cardiac signal, ΓI related to an irregularity sample entropy (SampEnI) indicative of the degree of cycle length irregularity of the cardiac signal, wherein SampEnI=−InΓI, the complexity analyzer including a complexity entropy computer adapted to compute a complexity parameter ΓC indicative of a degree of morphological complexity of the cardiac signal, ΓC related to a complexity sample entropy (SampEnC) indicative of the degree of morphological complexity of the cardiac signal, wherein SampEnC=−InΓC; and an arrhythmia classifier coupled to the irregularity analyzer and the complexity analyzer, the arrhythmia classifier adapted to classify the detected arrhythmia episode using the irregularity parameter and the complexity parameter.