| 摘要 |
This invention relates to compounds of Formula (I), (II), or (III) as shown in the specification, which contain a 1,5-diphenylpenta-1,4-dien-3-one backbone. These compounds can be used to treat cancer, inflammatory disease, or autoimmune disease. |
| 主权项 |
1. A compound of the following formula:wherein
each of X and Y, independently, is H, alkyl, or halo; and each of R1, R2, R3, R4, R5, R1′, R2′, R3′, R4′, and R5′, independently, is H, alkyl, halo, OH, Rc—O—, RdS(O)2—O—, (Rd)2P(O)—O—, or (RdO)2P(O)—O—, Rc being unsubstituted alkyl or alkyl substituted with halo, OH, alkoxy, amino, or cycloalkyl, and Rd being H, OH, C2-C10 alkyl, or alkoxy; in which at least one of R1, R2, R3, R4, R5, R1′, R2′, R3′, R4′, and R5′ is RdS (O)2—O—, (Rd)2P(O)—O—, or (RdO)2P(O)—O—. |
