发明名称 |
Method of preparing polymeric adhesive compositions utilizing the mechanism of interaction between the polymer components |
摘要 |
A method of selecting components for use in water-absorbing pressure-sensitive adhesive compositions is provided. The method involves selecting a film-forming polymer, a ladder-like non-covalent crosslinker that is capable of forming a ladder-like interpolymer complex with the film-forming polymer selected, and selecting a carcass-like non-covalent crosslinker that is capable of forming a carcass-like complex with at least one of the film-forming polymer selected or the ladder-like non-covalent crosslinker selected. The adhesive hydrogels provide high adhesion in a swollen state and bridge the gap between conventional pressure sensitive adhesives and bioadhesives. Methods for preparing and using the resulting compositions are also disclosed. |
申请公布号 |
US8821901(B2) |
申请公布日期 |
2014.09.02 |
申请号 |
US201012754331 |
申请日期 |
2010.04.05 |
申请人 |
A.V. Topchiev Institute of Petrochemical Synthesis Russian Academy of Sciences;Corium International, Inc. |
发明人 |
Feldstein Mikhail M.;Bairamov Danir F.;Platé Nicolai A.;Kulichikhin Valery G.;Chalykh Anatoly E.;Cleary Gary W.;Singh Parminder |
分类号 |
A61K8/02;A61K8/18;A61Q11/00;A01N39/00;A61K33/40;A61K6/00 |
主分类号 |
A61K8/02 |
代理机构 |
McDermott Will & Emery LLP |
代理人 |
Evans Susan T.;McDermott Will & Emery LLP |
主权项 |
1. A method of preparing a bioadhesive, tooth whitening composition comprising:
(i) blending a mixture comprising a (1:1) methyacrylic acid-ethyl acrylate copolymer, polyvinylpyrrolidone, poly(ethylene glycol) having a molecular weight from 200-600, and a tooth whitening agent, to thereby form a blended polymer-tooth whitening agent composition, wherein the amount of polyvinylpyrrolidone on a weight basis is greater than the amount of the methyacrylic acid-ethyl acrylate copolymer or the amount of the poly(ethylene)glycol, (ii). melting the blended polymer-tooth whitening agent composition from (i) to form a melted composition, and (iii). extruding the melted composition from (ii) to form an extruded tooth whitening composition, the extruded tooth whitening composition comprising from about 20-95 wt % polyvinylpyrrolidone, from about 0.5-40 wt % of methyacrylic acid-ethyl acrylate copolymer, and from about 0.5-60 wt % poly(ethylene glycol). |
地址 |
Moscow RU |