发明名称 Complex combining an organic silicon derivative with hyaluronic and acid calibrated fragments, for preventive and repairing action of cutaneous damages
摘要 The invention concerns a complex based on an organic silicon derivative. The invention is characterized in that said derivative is combined, by weak bonds, with one or several hyaluronic acid calibrated fragments of molecular weight comprised between 150 and 750 kDa, said derivative being of general formula (I): RxSi(OH)4-x, (I) wherein: R is a (C1-C4)alkyl, and x=1 or 2. The invention also concerns the use of such a complex in the prevention or the repair of cutaneous damages.
申请公布号 US8822433(B2) 申请公布日期 2014.09.02
申请号 US201213649640 申请日期 2012.10.11
申请人 Exsymol S.A.M. 发明人 Seguin Marie-Christine
分类号 A61K31/728;C07F7/08;C08B37/00;A61K8/73;A61K31/695;C08B37/08;A61K8/58;A61Q19/08 主分类号 A61K31/728
代理机构 Volpe and Koenig, P.C. 代理人 Volpe and Koenig, P.C.
主权项 1. A method of cosmetic care for repairing skin aging damage to a patient in need of boosting epidermal cell activity and limiting pro-inflammatory adverse effect of hyaluronic acid fragments produced by catabolic action of cutaneous tissue, the method comprising applying on a skin, a complex based on: an organic silicon derivative combined withone or several hyaluronic acid calibrated fragments of molecular weight between 150 and 600 kDa,said derivative being of formula (1): RxSi(OH)4-x  (I),wherein R is a (C1-C4)alkyl, and x=1 or 2.
地址 Monaco MC