发明名称 |
Collagenase enzyme containing formulation useful for treatment of a fibrotic chronic total occlusion |
摘要 |
<p>The use of a collagenase containing formulation for degrading collagen within an occlusive atherosclerotic plaque in a chronic fibrotic occlusion, chronically occluded animal tube or cavity. A medical-related apparatus is provided comprising a medical-related device having provided thereto a therapeutic amount of a collagen degrading composition comprising a proteiolytic enzyme containing formulation A method is provided for treating chronically occluded animal tubes and cavities by administering a therapeutic effective amount of a proteolytic enzyme-containing formulation adjacent to an occluding atherosclerotic plaque, waiting for a pre-angioplasty waiting period, followed by crossing the plaque with an angioplasty guide wire.</p> |
申请公布号 |
IL161137(A) |
申请公布日期 |
2014.08.31 |
申请号 |
IL20040161137 |
申请日期 |
2004.03.29 |
申请人 |
MATRIZYME PHARMA CORPORATION;BRADLEY H. STRAUSS |
发明人 |
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分类号 |
A01K67/027;A61K;A61B17/12;A61D1/00;A61D7/00;A61K38/46;A61K38/48;A61K38/51;A61L;A61P;A61P7/02;A61P9/10 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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