发明名称 Methods for purifying proteins having fc regions
摘要 <p>The present application provides methods of purifying A² binding proteins having a Fc region, for example, anti-A² antibodies or antibody fusions, by adsorbing the A² binding protein to a Fc binding agent, such as, for example, Protein A or Protein G, followed by a wash with a divalent cation salt buffer to remove impurities and subsequent recovery of the adsorbed A² binding protein. The present application also features methods of eluting the purified A² binding protein as well as the incorporation of the methods within a purification train. Kits comprising components for carrying out the methods and instructions for use are also provided.</p>
申请公布号 IL187642(A) 申请公布日期 2014.08.31
申请号 IL20070187642 申请日期 2007.11.26
申请人 WYETH LLC 发明人
分类号 C07K 主分类号 C07K
代理机构 代理人
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