发明名称 |
TRISUBSTITUTED 1,2,4-TRIAZOLES 124- |
摘要 |
The present invention relates to substituted 1-(alkyl)-3-aniline-5-aryl triazole derivatives and analogues or pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, according to Formula (I). The invention particularly relates to potent positive allosteric modulators of nicotinic acetylcholine receptors which have the capability of increasing the efficacy of nicotinic receptor agonists. |
申请公布号 |
HK1146281(A1) |
申请公布日期 |
2014.08.29 |
申请号 |
HK20110100474 |
申请日期 |
2011.01.18 |
申请人 |
JANSSEN PHARMACEUTICA NV |
发明人 |
THURING, JOHANNES WILHELMUS JOHN F.;DINKLO, THEODORUS;LESAGE, ANNE SIMONE JOSEPHINE;DE BRUYN, MARCEL FRANS LEOPOLD;ZHUANG, WEI |
分类号 |
C07D;A61K;A61P |
主分类号 |
C07D |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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