发明名称 |
Formulations of Deoxycholic Acid and Salts Thereof |
摘要 |
<p>The present application is directed to an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid, wherein the composition is maintained at a pH from about 8.1 to about 8.5 such that the composition is stabilized against precipitation. Also disclosed herein, are methods for stabilizing an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid against precipitation, said method comprising maintaining pH of the solution from about 8.1 to about 8.5.</p> |
申请公布号 |
SI2561876(T1) |
申请公布日期 |
2014.08.29 |
申请号 |
SI20110030212T |
申请日期 |
2011.08.23 |
申请人 |
KYTHERA BIOPHARMACEUTICALS, INC. |
发明人 |
HODGE ROBERT EMIL;WEBSTER JEFFREY DOUGLAS;MORIARTY ROBERT M. |
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