| 摘要 |
Disclosed is the use of spray-dried first microparticles that comprise human fibrinogen and spray-dried second microparticles that comprise human thrombin for the manufacture of a medicament for use as a haemostat in the topical treatment of a mild or moderate bleeding wound, with a time to haemostasis of less than five minutes wherein the wound is selected from minor abrasions, cuts, scrapes, scratches, burns, sunburns, ulcers, internal venous bleeding, external venous bleeding, and surgical interventions selected from those involving the gastrointestinal system, on parenchymal organs; surgical interventions in the ear, nose and throat area (ENT) cardiovascular surgery, aesthetic surgery, spinal surgery, neurological surgery; lymphatic, biliary, and cerebrospinal (CSF) fistulae, air leakages during thoracic and pulmonary surgery, thoracic surgery, orthopaedic surgery; gynaecological surgical procedures; vascular surgery and emergency surgery. |
