发明名称 |
ERBB2 Peptides |
摘要 |
Compositions that inhibit or block the interaction between Erbin and ErbB2 and methods of their use are provided. Preferred compositions include peptides that inhibit or block Erbin and ErbB2 interaction under physiologic conditions in a subject. One embodiment provides an isolated peptide fragment of ErbB2 including the C-terminal 15 amino acids of ErbB2. The peptide fragment can be about 15 to 27 amino acids in length. |
申请公布号 |
US2014243268(A1) |
申请公布日期 |
2014.08.28 |
申请号 |
US201414188318 |
申请日期 |
2014.02.24 |
申请人 |
Georgia Regents Research Institute, Inc. |
发明人 |
Mei Lin;Xiong Wen-Cheng;Shen Cheng-Yong;Tao Yan-Mei;Luo Shi-Wen |
分类号 |
C07K14/71;C07K7/08 |
主分类号 |
C07K14/71 |
代理机构 |
|
代理人 |
|
主权项 |
1. An isolated peptide fragment of ErbB2 comprising the C-terminal 15 amino acids of ErbB2. |
地址 |
Augusta GA US |