发明名称 |
COMPOUNDS, COMPOSITIONS, AND METHODS FOR PREVENTING METASTASIS OF CANCER CELLS |
摘要 |
Disclosed are methods for preventing metastasis of cancer cells. The disclosed compounds can be used to prevent the spread of tumor or other types of cancer cells. |
申请公布号 |
US2014242026(A1) |
申请公布日期 |
2014.08.28 |
申请号 |
US201414272689 |
申请日期 |
2014.05.08 |
申请人 |
Aerpio Therapeutics Inc. |
发明人 |
Shalwitz Robert;Peters Kevin Gene |
分类号 |
C07D277/28;A61K38/20;A61K31/7068;A61K31/517;A61K31/65;A61K31/4375;A61K39/395;A61K31/426;C07D417/04;A61K31/427;A61K31/497;A61K31/4439;C07D277/64;A61K31/428;C07D417/12;C07D417/14;A61K31/538;A61K31/337 |
主分类号 |
C07D277/28 |
代理机构 |
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代理人 |
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主权项 |
1. A method for reducing the volume of a tumor in a subject, comprising administering to the subject a compound of the formula: wherein R is a thiazolyl unit having the formula: R2 and R4 are each chosen from: i) substituted or unsubstituted C1-C6 linear, C3-C6 branched, or C3-C6 cyclic alkyl; iii) substituted or unsubstituted phenyl; or iv) substituted or unsubstituted thiophenyl; R1 is C1-C6 linear, C3-C6 branched or C3-C6 cyclic alkoxy; or a pharmaceutically acceptable salt thereof. |
地址 |
Cincinnati OH US |