| 发明名称 |
Acid Addition Salt of Donepezil and Pharmaceutical Composition Thereof |
| 摘要 |
Disclosed is an acid addition salt of donepezil, wherein acid counterion is selected from the group consisting of pamoic acid, cypionic acid, camphor sulfonic acid, enanthic acid, fusidic acid, gluceptic acid, gluconic acid, lactobionic acid, lauric acid, valeric acid, Dibenzoyl-D-Tartaric acid and terephthalic acid. Disclosed is a process for the preparation and pharmaceutical composition comprising the same. More specifically, disclosed is concerned with the pamoate acid addition salts of donepezil. Disclosed also is long acting formulation comprising the acid addition salt of donepezil and process for the preparation thereof. |
| 申请公布号 |
US2014243278(A1) |
申请公布日期 |
2014.08.28 |
| 申请号 |
US201214131178 |
申请日期 |
2012.07.03 |
| 申请人 |
Nadkarni Sunil Sadanand;Gupta Arunkumar;Abraham Jaya;Parikh Manish;Suthar Mahesh;Manavadariya Bipin;Mishra Vivek |
发明人 |
Nadkarni Sunil Sadanand;Gupta Arunkumar;Abraham Jaya;Parikh Manish;Suthar Mahesh;Manavadariya Bipin;Mishra Vivek |
| 分类号 |
C07D211/32;C07C65/01;C07C57/15;C07C59/70;C07C65/11;C07C309/19 |
主分类号 |
C07D211/32 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An acid addition salt of donepezil, wherein the acid counterion is selected from the group consisting of pamoic acid, cypionic acid, camphor sulfonic acid, enanthic acid, fusidic acid, gluceptic acid, gluconic acid, lactobionic acid, lauric acid, valeric acid, Dibenzoyl-D-Tartaric acid and terephthalic acid. |
| 地址 |
Gandhinagar IN |
