发明名称 CIS-MORPHOLINONE AND OTHER COMPOUNDS AS MDM2 INHIBITORS FOR THE TREATMENT OF CANCER
摘要 The present invention provides MDM2 inhibitor compounds of Formula (I), or the pharmaceutically acceptable salts thereof, wherein the variables are defined above, which compounds are useful as therapeutic agents, particularly for the treatment of cancers. The present invention also relates to pharmaceutical compositions that contain an MDM2 inhibitor.
申请公布号 WO2014130470(A1) 申请公布日期 2014.08.28
申请号 WO2014US16971 申请日期 2014.02.18
申请人 AMGEN INC. 发明人 BARTBERGER, MICHAEL, D.;BECK, HILARY, PLAKE;DEGRAFFENREID, MICHAEL, R.;FOX, BRIAN, M.;GONZALEZ LOPEZ DE TURISO, FELIX;JULIAN, LISA, D.;KAYSER, FRANK;MEDINA, JULIO, C.;OLSON, STEVEN, H.;REW, YOSUP;ROVETO, PHILIP, M.;SUN, DAQING;YAN, XUELEI
分类号 C07D265/32;A61K31/5375;A61K31/5377;A61K31/54;A61P35/00;C07D279/12;C07D413/04;C07D413/06 主分类号 C07D265/32
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