Disclosed are compounds of Formula (I) and/or a salt thereof; wherein R is -OH or -OP(O)(OH)2. Also disclosed are methods of using such compounds as selective agonists for G protein-coupled receptor S1P1, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.
申请公布号
WO2014130752(A2)
申请公布日期
2014.08.28
申请号
WO2014US17534
申请日期
2014.02.21
申请人
BRISTOL-MYERS SQUIBB COMPANY
发明人
DHAR, T. G. MURALI;XIAO, HAI-YUN;DYCKMAN, ALARIC J.;CHAN, ERIC J.;DABROS, MARTA;ROBERTS, DANIEL RICHARD