发明名称 |
VACCINE COMPOSITION |
摘要 |
There is described a kit for use in inducing an immune response in a mammal, the kit includes: a first virus that expresses MAGEA3, Human Papilloma Virus E6/E7 fusion protein, human Six-Transmembrane Epithelial Antigen of the Prostate protein, or Cancer Testis Antigen 1, or a variant thereof as an antigenic protein and that is formulated to generate an immunity to the protein or variant thereof in the mammal. The kit also includes a Maraba MG1 virus encoding the same antigen, or a variant of the same antigen. The Maraba MG1 virus is formulated to induce the immune response in the mammal. The first virus is immunologically distinct from the Maraba MG1 virus. |
申请公布号 |
CA2901501(A1) |
申请公布日期 |
2014.08.28 |
申请号 |
CA20142901501 |
申请日期 |
2014.02.20 |
申请人 |
CHILDREN'S HOSPITAL OF EASTERN ONTARIO RESEARCH INSTITUTE INC.;OTTAWA HOSPITAL RESEARCH INSTITUTE;MCMASTER UNIVERSITY |
发明人 |
STOJDL, DAVID F.;BELL, JOHN C.;LICHTY, BRIAN;POL, JONATHAN |
分类号 |
C12N7/01;A61K35/76;A61K39/00;A61P35/00;A61P37/04;C07K14/145;C07K14/47;C07K19/00;C12N15/113;C12N15/12;C12N15/47;C12N15/62;C12N15/86 |
主分类号 |
C12N7/01 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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