发明名称 |
METHOD FOR PRODUCING TRICYCLIC COMPOUND, AND TRICYCLIC COMPOUND CAPABLE OF BEING PRODUCED BY SAID PRODUCTION METHOD |
摘要 |
<p>The purpose of the present invention is to provide a method for producing, with a high yield and high reproducibility, a tricyclic compound containing pyrrolopyridine rings while minimizing byproduct generation, and a novel tricyclic compound capable of being obtained by said method. The present invention provides a method for producing a compound represented by formula (1), or a salt thereof, the method comprising: step [I] of reacting an organoborane reagent with a compound represented by formula (2), or a salt thereof; and step [II] of inducing intramolecular cyclization in the reaction product of step [I] by using a zero-valency palladium catalyst in the presence of an alkali metal hydroxide.</p> |
申请公布号 |
CA2898274(A1) |
申请公布日期 |
2014.08.28 |
申请号 |
CA20142898274 |
申请日期 |
2014.02.21 |
申请人 |
TAIHO PHARMACEUTICAL CO., LTD. |
发明人 |
UNO, TAKAO;SHIMAMURA, TADASHI |
分类号 |
C07D487/14;C07B61/00;C07F7/18 |
主分类号 |
C07D487/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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