| 发明名称 |
TREATMENTS FOR MYCOBACTERIUM TUBERCULOSIS |
| 摘要 |
The technology described herein relates to treatments for tuberculosis which target the ClpP1P2 protease complex, including ClpC1. Further embodiments relate to assays and screens for modulators of the ClpP1P2 protease complex, including ClpC1. |
| 申请公布号 |
US2014243255(A1) |
申请公布日期 |
2014.08.28 |
| 申请号 |
US201214352440 |
申请日期 |
2012.10.19 |
| 申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
Kandror Olga;Goldberg Alfred Lewis;Akopian Tatos;Rubin Eric J.;Raju Ravikiran M. |
| 分类号 |
A61K38/55;C12Q1/37;A61K31/70;C07K5/08;A61K31/055;C12N15/113 |
主分类号 |
A61K38/55 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treating a Mycobacterium tuberculosis infection comprising administering to a subject a composition comprising an inhibitor of ClpP1P2 protease. |
| 地址 |
Cambridge MA US |
