摘要 |
The invention relates to methods for determining the sequence of a genomic region of interest comprising a target nucleotide sequence comprising, providing a DNA comprising a genomic region of interest, fragmenting the DNA, separating the DNA fragments, fragmenting and ligating the DNA fragments to provide for ligated fragments of the DNA fragments (or ligated DNA subfragments), and determining at least part of the sequences of at least part of the ligated DNA subfragments which comprise the target nucleotide sequence. |