发明名称 |
Method of producing a polypeptide or virus of interest in a continuous cell culture |
摘要 |
Described herein is a chemostat-like continuous cell culture system that combines certain advantages of perfusion open systems and chemostat open systems to improve the culturing of mammalian cells, e.g., genetically modified cells, particularly in serum-free or chemically-defined media. The continuous culture system described herein involves culturing mammalian cells in a continuous cell culture system, which comprises a cell retention device, wherein the cell culture system has a dilution rate (D) of less than about 2 d |
申请公布号 |
AU2010277490(B2) |
申请公布日期 |
2014.08.28 |
申请号 |
AU20100277490 |
申请日期 |
2010.08.02 |
申请人 |
BAXTER HEALTHCARE S.A.;BAXTER INTERNATIONAL INC. |
发明人 |
GRILLBERGER, LEOPOLD;REITER, MANFRED;FLEISCHANDERL, DANIEL |
分类号 |
C12M3/00;C12N5/00 |
主分类号 |
C12M3/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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