| 发明名称 |
Granular Pharmaceutical Composition |
| 摘要 |
The present invention relates to a granular pharmaceutical composition obtained by coating a nucleus with: (1) a layer containing a material having a damp-proofing function, and (2) a drug layer containing linaclotide, a pharmaceutically acceptable salt, or a hydrate thereof, and (3) a layer containing a material having a damp-proofing function. Also, the present invention relates to a method for manufacturing the granular pharmaceutical composition obtained by coating the nucleus with (1) the layer containing the material having a damp-proofing function, (2) the drug layer containing the linaclotide, the pharmaceutically acceptable salt, or the hydrate thereof, and (3) the layer containing the material having a damp-proofing function. |
| 申请公布号 |
US2014242158(A1) |
申请公布日期 |
2014.08.28 |
| 申请号 |
US201214348110 |
申请日期 |
2012.09.28 |
| 申请人 |
Astellas Pharma, Inc. |
发明人 |
Nishiura Mare;Ashihara Kenichi;Imai Kanehira;Muro Atsushi;Nishikawahara Tsukasa |
| 分类号 |
A61K9/16;A61K9/20;A61K9/48;A61K38/10 |
主分类号 |
A61K9/16 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A granular pharmaceutical composition obtained by coating a core with (1) a layer containing a substance exhibiting moisture-proofing action, (2) a drug layer containing linaclotide, a pharmaceutically acceptable salt thereof, or a hydrate of either, and (3) a layer containing a substance exhibiting moisture-proofing action. |
| 地址 |
Tokyo JP |
