ADENINE DERIVATIVES HAVING IMMUNOMODULATING ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY

摘要

The compound 2-[1-(6-aminopurin-9-yl)-2-oxoethoxy]prop-2-enal of formula (I), its monohydrate of formula (II), or its corresponding cyclic monohydrate of formula (III), in which the stereochemical chiral center indicated with an asterisk can be R (Rectus), S (Sinister) or racemic, including the tautomers of the adenine ring and the pharmaceutically acceptable salts, are used in the treatment of inflammatory disorders or of pain disorders.

主权项

1. The compound 2-[1-(6-aminopurin-9-yl)-2-oxo-ethoxy]prop-2-enal of formula: its monohydrate of formula (II): or its corresponding cyclic monohydrate of formula: wherein the stereochemical chiral centre indicated with an asterisk can be R (Rectus), S (Sinister) or racemic, including tautomers of the adenosine ring and its pharmaceutically acceptable salts, for use in the treatment of inflammatory pathologies or pain pathology.