COMPOUNDS INHIBITING GALECTIN-1 EXPRESSION, CANCER CELL PROLIFERATION, INVASION, AND TUMORIGENESIS

摘要

Disclosed herein are compositions comprising a galectin-1-targeting compound in a therapeutically effective composition for treating cancer. In an aspect, a galectin-1-targeting compound is OTX-008. Also disclosed herein are methods of making and using such compositions.

主权项

1. A method of inhibiting a galectin-1-associated pathway in a mammalian cell, the method comprising contacting a mammalian cell with an effective amount of a galectin-1-targeting compound.