The present invention relates to dihydropteridinones, their use as modulators of γ-secretase and to pharmaceutical compositions containing said compounds. In particular, the present invention relates to compounds which interfere with γ-secretase and/or its substrate and therefore modulate the formation of &Agr;&bgr; peptides.
申请公布号
WO2014127815(A1)
申请公布日期
2014.08.28
申请号
WO2013EP53403
申请日期
2013.02.21
申请人
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
发明人
GERLACH, KAI;EICKMEIER, CHRISTIAN;HEINE, CLAUDIA;HEINE, NIKLAS;WEBER, ALEXANDER