发明名称 |
SERPINS: METHODS OF THERAPEUTIC BETA-CELL REGENERATION AND FUNCTION |
摘要 |
Compositions and methods of use are provided for improving &bgr; cell function and promoting pancreatic &bgr; cell proliferation in vitro, in vivo and ex vivo. The active agents of the pending invention comprise Serpin family peptides (e.g., SerpinB1), functional and structural analogs of Serpin family peptides and nucleic acids encoding Serpin family peptides, as well as active fragments thereof. |
申请公布号 |
WO2014128257(A1) |
申请公布日期 |
2014.08.28 |
申请号 |
WO2014EP53419 |
申请日期 |
2014.02.21 |
申请人 |
SANOFI;JOSLIN DIABETES CENTER |
发明人 |
MARGERIE, DANIEL;LOHMANN, MATTHIAS;GUILLEMOT, JEAN CLAUDE;LOYAUX, DENIS;KULKARNI, ROHIT;EL OUAAMARI, ABDELFATTAH |
分类号 |
A61K38/57;A61P3/10 |
主分类号 |
A61K38/57 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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