发明名称 |
HETEROCYCLIC GSK-3 ALLOSTERIC MODULATORS |
摘要 |
The invention relates to heterocyclic derivatives of substituted quinolines as allosteric inhibitors of the glycogen synthase kinase 3 (GSK-3) enzyme. Thus, said compounds can be used in the production of a drug for the treatment and/or prevention of diseases in which GSK-3 is involved, such as: neurodegenerative diseases, inflammatory diseases, cancer and diabetes, as well as to promote a plurality of regenerative processes.. |
申请公布号 |
EP2769720(A1) |
申请公布日期 |
2014.08.27 |
申请号 |
EP20120836243 |
申请日期 |
2012.09.28 |
申请人 |
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) |
发明人 |
MARTÍNEZ GIL, ANA;GIL AYUSO-GONTÁN, CARMEN;PALOMO RUIZ, VALLE;PEREZ MARTÍN, CONCEPCIÓN;PÉREZ FERNÁNDEZ, DANIEL I.;REYES RODRÍGUEZ, JULIO ALBERTO |
分类号 |
A61K31/435;A61K31/4704;C07D215/56 |
主分类号 |
A61K31/435 |
代理机构 |
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地址 |
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