发明名称 USE OF CHIMERIC ANTIGEN RECEPTOR-MODIFIED T CELLS TO TREAT CANCER
摘要 The present invention provides compositions and methods for treating cancer in a human. The invention includes relates to administering a genetically modified T cell to express a CAR wherein the CAR comprises an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain.
申请公布号 ZA201304470(B) 申请公布日期 2014.08.27
申请号 ZA20130004470 申请日期 2013.06.18
申请人 THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 发明人 JUNE CARL H;LEVINE BRUCE L;PORTER DAVID L;KALOS MICHAEL D;MILONE MICHAEL C
分类号 C07H;A61K 主分类号 C07H
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