发明名称 |
AMINE CATIONIC LIPIDS AND USES THEREOF |
摘要 |
The present invention relates to lipid compounds and uses thereof. In particular, the compounds include a class of cationic lipids having an amine moiety, such as an amino-amine or an amino-amide moiety. The lipid compounds are useful for in vivo or in vitro delivery of one or more agents (e.g., a polyanionic payload or an antisense payload, such as an RNAi agent). |
申请公布号 |
EP2768958(A1) |
申请公布日期 |
2014.08.27 |
申请号 |
EP20120841768 |
申请日期 |
2012.10.18 |
申请人 |
DICERNA PHARMACEUTICALS INC. |
发明人 |
BROWN, BOB, DALE;BASU, SUJIT, KUMAR;SCHWARTZ, DAVID;FRASER, ALLISTER |
分类号 |
C12N15/11;A61K9/127;A61K38/54;C07C211/09;C07C211/11;C07C211/13;C07C211/14;C07C237/06;C07D211/36;C07D233/61;C07D233/64;C07D239/42;C07D241/04;C07D295/03;C07D295/13;C07D295/15 |
主分类号 |
C12N15/11 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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