发明名称 |
COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS |
摘要 |
<p>The invention provides novel pyrimidine and pyridine derivatives and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine and pyridine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kinase (ALK) activity, focal adhesion kinase (FAK), zeta-chain-associated protein kinase 70 (ZAP-70), insulin-like growth factor (IGF-1R), or a combination thereof.</p> |
申请公布号 |
EP2091918(B1) |
申请公布日期 |
2014.08.27 |
申请号 |
EP20070864693 |
申请日期 |
2007.11.20 |
申请人 |
IRM LLC |
发明人 |
MICHELLYS, PIERRE-YVES;PEI, WEI;MARSILJE, THOMAS H.;CHEN, BEI;UNO, TETSUO |
分类号 |
C07D213/74;C07D239/48;C07D239/95;C07D401/12 |
主分类号 |
C07D213/74 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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