MÉTODO PARA PRESERVAR PARTÍCULAS VIRAIS, EXCIPIENTE PARA A PRESERVAÇÃO DE PARTÍCULAS VIRAIS, USO DE UM EXCIPIENTE, KIT, MÉTODO PARA PREPARAR UMA VACINA, E, PÓ SECO.

摘要

A method for preserving viral particles comprises: (i) providing an aqueous solution of one or more sugars, a polyethyleneimine and said viral particles wherein the concentration of polyethyleneimine is 15μM or less based on the number-average molar mass (Mn) of the polyethyleneimine and the sugar concentration or, if more than one sugar is present, total sugar concentration is greater than 0.1 M; and (ii) drying the solution to form an amorphous solid matrix comprising said viral particles.