发明名称 Anti viral therapy
摘要 The present invention provides a method of identifying host cell molecules which may be modulated to inhibit viral replication and method of testing antiviral compounds. In addition, the invention provides compositions, methods and medicaments for treating viral infections and/or diseases or conditions caused or contributed to by viruses.
申请公布号 US8815820(B2) 申请公布日期 2014.08.26
申请号 US201013262086 申请日期 2010.03.30
申请人 The University Court of the University of Edinburgh 发明人 Buck Amy
分类号 A61K48/00;C07H21/02;C07H21/04 主分类号 A61K48/00
代理机构 Myers Bigel Sibley & Sajovec, P.A. 代理人 Myers Bigel Sibley & Sajovec, P.A.
主权项 1. A method of treating a subject having one or more viral infections, viral diseases and/or viral conditions, said method comprising the steps of administering a pharmaceutically effective amount of a multi-species antiviral microRNA (miRNA) capable of modulating or mimicking the expression, function and/or activity of a host cell miRNA molecule, wherein the host cell miRNA is miR-199a having the nucleotide sequence of SEQ ID NO:14.
地址 Edinburgh GB