发明名称 Fungicidal heterocyclic carboxamides
摘要 Disclosed are compounds of Formula 1, including all stereoisomers, N-oxides, and salts thereof,; wherein L is —C(R12a)R12b—C(R13a)R13b—, wherein the carbon atom bonded to R12a and R12b is also bonded to the carboxamide nitrogen atom in Formula 1; or 1,2-phenylene optionally substituted with up to 4 substituents independently selected from halogen and C1-C2 alkyl;and A, Z, R1, R2, n, G and Q are as defined in the disclosure.;Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling plant disease caused by a fungal pathogen comprising applying an effective amount of a compound or a composition of the invention. Also disclosed are methods for controlling a phytophagous nematode comprising contacting the nematode or its environment with a nematocidally effective amount of a compound of Formula 1 wherein L is —C(R12a)R12b—C(R13a)R13b; and A, Z, R1, R2, n, G and Q are as defined in the disclosure.
申请公布号 US8815772(B2) 申请公布日期 2014.08.26
申请号 US201313921495 申请日期 2013.06.19
申请人 E I du Pont de Nemours and Company 发明人 Bereznak James Francis;Gutteridge Steven;Reddy Ravisekhara P;Taggi Andrew Edmund;Campbell Matthew James;Kar Moumita;Desaeger Johan A. J.
分类号 A01N25/00;A01N43/40;C07D401/00;A01N43/56 主分类号 A01N25/00
代理机构 代理人
主权项 1. A compound selected from Formula 1, N-oxides and salts thereof,wherein A is a radical selected from the group consisting of R1 is H, cyclopropyl or C1-C2 alkoxy; Z is O or S; L is —C(R12a)R12b—C(R13a)R13b—, wherein the carbon atom bonded to R12a and R12b is also bonded to the carboxamide nitrogen atom in Formula 1; or 1,2-phenylene optionally substituted with up to 4 substituents independently selected from halogen and C1-C2 alkyl; G is N or C—R2a; each R2 is independently halogen, nitro, cyano, C1-C2 alkyl, C1-C2 haloalkyl, C1-C2 alkoxy or C1-C2 haloalkoxy; n is 0, 1, 2 or 3; R2a is H, halogen, nitro, cyano, C1-C2 alkyl, C1-C2 haloalkyl, C1-C2 alkoxy or C1-C2 haloalkoxy; B1 is CH or N; B2 is CH or N; R3 is halogen, C1-C3 alkyl or C1-C3 haloalkyl; R4 is halogen, C1-C3 alkyl or C1-C3 haloalkyl; R5 is H, halogen, C1-C3 alkyl or C1-C3 haloalkyl; R6 is C1-C2 alkyl; R7 is halogen, C1-C3 alkyl or C1-C3 haloalkyl; R8 is H, C1-C2 alkyl or C1-C2 haloalkyl; R9 is halogen, C1-C3 alkyl or C1-C3 haloalkyl; R10 is halogen, C1-C3 alkyl or C1-C3 haloalkyl; R11 is halogen, C1-C3 alkyl or C1-C3 haloalkyl; m is 0, 1 or 2; R12a and R12b are each independently H, C1-C2 alkyl or C1-C2 haloalkyl; R12a and R12b are taken together as C2-C4 alkanediyl; R13a is H, halogen, C1-C2 alkyl, C1-C2 haloalkyl, C1-C2 alkoxy, C1-C2 haloalkoxy, C1-C2 alkylthio or C1-C2 alkoxyamino; R13b is H, halogen, C1-C2 alkyl or C1-C2 haloalkyl; or R13a and R13b are taken together as C2-C4 alkanediyl; Q is a 5-membered unsaturated heterocyclic ring containing ring members selected from carbon atoms and up to 4 heteroatoms independently selected from up to 1O, up to 1S and up to 4N atoms, wherein up to 2 carbon atom ring members are independently selected from C(═O), the ring optionally substituted with one substituent on a ring member distal relative to the ring member connecting the heteroaromatic ring to the remainder of Formula 1, said optional substituent selected from R14c on carbon atom ring members and from R14n on nitrogen atom ring members, the heterocyclic ring further optionally substituted with substituents selected from R15c on carbon atom ring members and R15n on nitrogen atom ring members; each R14c is independently halogen, cyano, C1-C3 alkyl, C1-C3 haloalkyl, C1-C3 alkoxy, C1-C3 haloalkoxy, C2-C3 alkoxycarbonyl or C2-C4 alkylcarbonyl; or a phenyl ring optionally substituted with up to 5 substituents independently selected from R16; or a heteroaromatic ring optionally substituted with up to 4 substituents independently selected from R17c on carbon atom ring members and from R17n on nitrogen atom ring members; each R14n is independently C1-C3 alkyl, C1-C3 haloalkyl or C1-C3 alkoxy; or a phenyl ring optionally substituted with up to 5 substituents independently selected from R18; or a heteroaromatic ring optionally substituted with up to 4 substituents independently selected from R19c on carbon atom ring members and from R19n on nitrogen atom ring members; each R15c is independently halogen, C1-C3 alkyl, C1-C3 haloalkyl or C1-C3 alkoxy; each R15n is independently C1-C3 alkyl, C1-C3 haloalkyl or C1-C3 alkoxy; each R16, R17c, R18 and R19c is independently halogen, cyano, C1-C2 alkyl, C1-C2 haloalkyl, C1-C2 alkoxy or C1-C2 haloalkoxy; each R17n and R19n is independently C1-C2 alkyl, C1-C2 haloalkyl or C1-C2 alkoxy; R20 is halogen, C1-C3 alkyl or C1-C3 haloalkyl; R21 is halogen, C1-C3 alkyl or C1-C3 haloalkyl; and R22 is H, C1-C2 alkyl or C1-C2 haloalkyl; provided that the compound of Formula 1 is other than: 2-methyl-N-[2-[4-(1H-pyrazol-1-yl)phenyl]ethyl]-5-thiazolecarboxamide, N-[2-[4-(3,5-dimethyl-1H-pyrazol-1-yl)phenyl]ethyl]-1,3,5-trimethyl-1H-pyrazole-4-carboxamide, 2-bromo-N-[2-[4-(1H-pyrazol-1-yl)phenyl]ethyl]benzamide, 3-methyl-N-[2-[4-(1H-pyrazol-1-yl)phenyl]ethyl]-2-thiophenecarboxamide, 2-methyl-N-[2-[4-(1H-pyrazol-1-yl)phenyl]ethyl]benzamide, 2-iodo-N-[2-[4-(1H-pyrazol-1-yl)phenyl]ethyl]benzamide, 2-fluoro-N-[2-[4-(1H-pyrazol-1-yl)phenyl]ethyl]benzamide, 2-chloro-N-[2-[4-(1H-pyrazol-1-yl)phenyl]ethyl]benzamide, 5-chloro-1,3-dimethyl-N-[2-[4-(2-methyl-4-thiazolyl)phenyl]ethyl]-1H-pyrazole-4-carboxamide, 2-methyl-N-[2-[4-(2-methyl-4-thiazolyl)phenyl]ethyl]benzamide, 2-methyl-N-[2-[4-(2-methyl-4-thiazolyl)phenyl]ethyl]-3-furancarboxamide, 2-fluoro-N-[2-[4-(2-methyl-4-thiazolyl)phenyl]ethyl]benzamide, 2-bromo-N-[2-[4-(2-methyl-4-thiazolyl)phenyl]ethyl]benzamide, 2-iodo-N-[2-[4-(2-methyl-4-thiazolyl)phenyl]ethyl]benzamide, N-[2-[4-(2-methyl-4-thiazolyl)phenyl]ethyl]-2-(trifluoromethyl)benzamide, and 2-chloro-N-[2-[4-(2-methyl-4-thiazolyl)phenyl]ethyl]benzamide.
地址 Wilmington DE US
您可能感兴趣的专利