Method for production of antibody using ostrich

摘要

Disclosed is an antibody produced using an ostrich. Also disclosed is a method for producing the antibody. By using an ostrich, it becomes possible to produce antibodies (particularly antibodies for medical use), which have been hardly produced by using the mammals such as the mouse and the rat, homogeneously in a single body, in large quantities and in a simple manner. The method can overcome a disadvantage of lot-to-lot variation which may occur in the production of polyclonal antibodies using other animals.

主权项

1. A method of producing an ostrich antibody having binding specificity for a viral protein or a peptide thereof, comprising the steps of:
a. administering to an ostrich of 2.5 to 10 months of age a viral protein or a peptide fragment thereof as an antigen, b. permitting in vivo production of an ostrich antibody against the protein or the peptide fragment thereof, where the ostrich antibody specifically binds to the protein or the peptide fragment thereof, c. isolating the ostrich antibody from an ostrich fluid, and d. producing a polyclonal antibody having binding specificity for a viral protein or a peptide thereof.