发明名称 |
Diagnostic composition comprising plasma cations having superior safety profile |
摘要 |
The present invention relates to a new diagnostic X-ray composition which exhibits a superior cardiac safety profile. The composition comprises a non-ionic iodinated dimer in a pharmaceutically acceptable carrier. More particularly, the invention provides a diagnostic composition comprising a Compound I, a pharmaceutically acceptable carrier, and dissolved therein a sodium compound and a calcium compound providing a sodium ion concentration of 40-50 mM and a calcium ion concentration of 0.1-0.7 mM. The invention also relates to methods of imaging using such diagnostic compositions.; |
申请公布号 |
US8815210(B2) |
申请公布日期 |
2014.08.26 |
申请号 |
US201013497641 |
申请日期 |
2010.10.28 |
申请人 |
GE Healthcare AS |
发明人 |
Wistrand Lars-Göran;Thaning Mikkel;Newton Ben |
分类号 |
A61K49/00;A61K49/04 |
主分类号 |
A61K49/00 |
代理机构 |
|
代理人 |
Ji Yonggang |
主权项 |
1. A diagnostic composition comprising a Compound I a pharmaceutically acceptable carrier; and dissolved therein a sodium compound and a calcium compound providing a sodium ion concentration of 40-50 mM and a calcium ion concentration of 0.1-0.7 mM. |
地址 |
Oslo NO |