发明名称 RESPONSIVENESS TO ANGIOGENESIS INHIBITORS.
摘要 <p>The invention is concerned with a method of determining whether a patient is more suitably treated by a therapy with an angiogenesis inhibitor, such as bevacizumab, by determing the genotype of VEGF promoter gene and/or VEGFR2 gene. The invention further relates to a pharmaceutical composition comprising an angiogenesis inhibitor, such as bevacizumab, for the treatment of a patient suffering from cancer based on the genotype of VEGF promoter gene and/or VEGFR2 gene. The invention further relates to a method for improving the treatment effect of chemotherapy of a patient suffering from cancer by adding an angiogenesis inhibitor, such as bevacizumab, based on the genotype of VEGF promoter gene and/or VEGFR2 gene.</p>
申请公布号 MX2014002311(A) 申请公布日期 2014.08.26
申请号 MX20140002311 申请日期 2012.08.28
申请人 F. HOFFMANN-LA ROCHE AG 发明人 SANNE LYSBET DE HAAS;PAUL DELMAR;DIETHER LAMBRECHTS;STEFAN SCHERER
分类号 C12Q1/68 主分类号 C12Q1/68
代理机构 代理人
主权项
地址