发明名称 |
QUINAZOLINE BASED EGFR INHIBITORS CONTAINING A ZINC BINDING MOIETY |
摘要 |
The present invention relates to quinazoline containing zinc-binding moiety based derivatives of Formula (IV) below. These compounds have enhanced and unexpected properties as inhibitors of epidermal growth factor receptor tyrosine kinase (EGFR-TK) and are useful in the treatment of EGFR-TK related diseases and disorders such as cancer. These compounds may further act as HDAC inhibitors. |
申请公布号 |
KR101434164(B1) |
申请公布日期 |
2014.08.26 |
申请号 |
KR20137002341 |
申请日期 |
2007.09.10 |
申请人 |
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发明人 |
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分类号 |
A61K31/517;A61P35/00;C07D239/86;C07D239/94 |
主分类号 |
A61K31/517 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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