Drug delivery device and method

摘要

Many people need vascular access for procedures such as hemodialysis. It is desirable that this access remain open or patent for the entire duration of the course of treatments. A drug delivery device and methods of using the device are introduced that delivery drug to venous anastomosis of a synthetic vascular access shunt. In some embodiments this device serves as the shunt connecting the target artery and vein to create the vascular access shunt.

主权项

1. A device comprising:
a vascular access shunt having a wall, an inner lumen, and two or more ends adapted to connect to mammalian vasculature, the wall having a substantially permeable region between an outer surface and the inner lumen; and a structure having a reservoir enclosed between an external region and an inner membrane, wherein the structure is coupled with the outer surface such that the inner membrane covers the substantially permeable region, and wherein the inner membrane is more permeable than the external region to allow a drug disposed within the reservoir to move from the reservoir through the inner membrane and the substantially permeable region into the inner lumen.