| 发明名称 |
Methods and compositions related to targeting tumors and wounds |
| 摘要 |
Disclosed are compositions and methods useful for targeting tumors, sites of injury and blood clots. The compositions and methods are based on peptide sequences that selectively bind to and home to tumors, sites of injury and blood clots in animals. The disclosed targeting is useful for delivering therapeutic and detectable agents to tumors, sites of injury and blood clots. |
| 申请公布号 |
US8815804(B2) |
申请公布日期 |
2014.08.26 |
| 申请号 |
US200712162751 |
申请日期 |
2007.02.05 |
| 申请人 |
Sanford-Burnham Medical Research Institute |
发明人 |
Ruoslahti Erkki;Pilch Jan |
| 分类号 |
C07K7/00;C07K7/06;C07K7/64;C07K14/47;A61K38/08;A61K38/12;A61K38/16;A61K38/17;A61K51/08;A61K49/00;A61K49/08;A61K49/14;A61K47/48 |
主分类号 |
C07K7/00 |
| 代理机构 |
|
代理人 |
Mittler E. Stewart |
| 主权项 |
1. An isolated peptide comprising an amino acid segment comprising the amino acid sequence of SEQ ID NO: 1, an amino acid sequence at least 90% identical to the amino acid sequence of SEQ ID NO: 1, or the amino acid sequence of SEQ ID NO: 1 having one, two, or three conservative amino acid substitutions, wherein the peptide has a length of less than 100 residues, wherein the amino acid segment is circular. |
| 地址 |
La Jolla CA US |
