发明名称 Substituted oxindole derivatives and their use as vasopressin receptor ligands
摘要 The present invention relates to novel oxindole derivatives of the general formula (I); to medicaments comprising them and to their use for the prophylaxis and/or treatment of diseases.
申请公布号 US8815868(B2) 申请公布日期 2014.08.26
申请号 US200712521713 申请日期 2007.12.28
申请人 Abbott GmbH & Co. KG 发明人 Netz Astrid;Oost Thorsten;Geneste Herve;Braje Wilfried;Wernet Wolfgang;Unger Liliane;Hornberger Wilfried;Lubisch Wilfried
分类号 A61K31/496;A61K31/4545;C07D401/04;C07D401/14 主分类号 A61K31/496
代理机构 Michael Best & Friedrich LLP 代理人 Mueller Lisa V.;Michael Best & Friedrich LLP
主权项 1. A compound of the general formula (I)in which R1 is ethoxy; R2 is hydrogen; R3 is cyano; R4 is hydrogen; R5 is hydrogen, methoxy or ethoxy; R6 is hydrogen or methoxy; R7 is hydrogen, methyl, ethyl, n-propyl or isopropyl; X1 is —NH—; X2 is N or CH; X3 is N or CH; where X2 and X3 are not simultaneously N;and the pharmaceutically acceptable salts, and tautomeric forms thereof.
地址 Wiesbaden DE