发明名称 <i>Corynebacteria </i>strain having enhanced 5′-xanthosine monophosphate productivity and a method of producing 5′-xanthosine monophosphate using the same
摘要 Disclosed is a novel microorganism which has a malate dehydrogenase activity higher than that of a wild-type. Also, a recombinant vector which has the structure shown in the cleavage map of FIG. 1, a Corynebacteria strain transformed therewith, and a method of producing 5′-xanthosine monophosphate by culturing the transformed strain are disclosed.
申请公布号 US8815545(B2) 申请公布日期 2014.08.26
申请号 US200913140321 申请日期 2009.12.17
申请人 CJ CheilJedang Corporation 发明人 Cho Jinman;Kim Hye Won;Lee Jinman;Lee Ji-Hye;Oh Yoon Seok;Park Jang Hee
分类号 C12P19/30;C12N1/12;C12N9/04;C12P19/32 主分类号 C12P19/30
代理机构 Lathrop &amp; Gage LLP 代理人 Lathrop &amp; Gage LLP ;Trinque Brian C.;Wilkins Andrew T.
主权项 1. An isolated Corynebacteria ammoniagenes strain, which strain has a malate:quinone oxidoreductase activity higher than that of a wild-type Corynebacteria ammoniagenes, wherein the higher MQO activity is achieved by increasing the number of mqo gene copies encoding the malate dehydrogenase, or replacing or modifying a promoter of an mqo gene, wherein said mqo gene is the Corynebacteria ammoniagenes mqo gene.
地址 Seoul KR