发明名称 |
<i>Corynebacteria </i>strain having enhanced 5′-xanthosine monophosphate productivity and a method of producing 5′-xanthosine monophosphate using the same |
摘要 |
Disclosed is a novel microorganism which has a malate dehydrogenase activity higher than that of a wild-type. Also, a recombinant vector which has the structure shown in the cleavage map of FIG. 1, a Corynebacteria strain transformed therewith, and a method of producing 5′-xanthosine monophosphate by culturing the transformed strain are disclosed. |
申请公布号 |
US8815545(B2) |
申请公布日期 |
2014.08.26 |
申请号 |
US200913140321 |
申请日期 |
2009.12.17 |
申请人 |
CJ CheilJedang Corporation |
发明人 |
Cho Jinman;Kim Hye Won;Lee Jinman;Lee Ji-Hye;Oh Yoon Seok;Park Jang Hee |
分类号 |
C12P19/30;C12N1/12;C12N9/04;C12P19/32 |
主分类号 |
C12P19/30 |
代理机构 |
Lathrop & Gage LLP |
代理人 |
Lathrop & Gage LLP ;Trinque Brian C.;Wilkins Andrew T. |
主权项 |
1. An isolated Corynebacteria ammoniagenes strain, which strain has a malate:quinone oxidoreductase activity higher than that of a wild-type Corynebacteria ammoniagenes, wherein the higher MQO activity is achieved by increasing the number of mqo gene copies encoding the malate dehydrogenase, or replacing or modifying a promoter of an mqo gene, wherein said mqo gene is the Corynebacteria ammoniagenes mqo gene. |
地址 |
Seoul KR |