发明名称 Inhibiting striated muscle activator of RHO (stars) to improve glycemic control
摘要 Described are methods of improving glycemic control/improving insulin sensitivity by administering an inhibitor of Striated Muscle Activator of Rho Signaling (STARS) activity, and methods of identifying new compounds for use in the described methods of treatment.
申请公布号 US8815799(B2) 申请公布日期 2014.08.26
申请号 US201113701082 申请日期 2011.06.03
申请人 Joslin Diabetes Center, Inc. 发明人 Patti Mary Elizabeth;Jin Wanzhu;Goldfine Allison B.
分类号 C12N9/00;C12N15/82;C12N15/113 主分类号 C12N9/00
代理机构 Pierce Atwood LLP 代理人 Pierce Atwood LLP ;Farrell Kevin M.;Wilson David J.
主权项 1. A method for improving glycemic control in a subject in need thereof, the method comprising administering a therapeutically effective amount of an inhibitor of MLK1-dependent SRF transcriptional activity.
地址 Boston MA US