| 摘要 |
The present invention provides a prophylactic or therapeutic agent and a prophylactic or therapeutic method superior in the prophylaxis or treatment of Sjogren's syndrome. Provided are a prophylactic or therapeutic agent for Sjogren's syndrome, containing a compound represented by the formula (I):;
wherein each symbol is as defined in the Specification, or a pharmaceutically acceptable salt thereof, and a method for the prophylaxis or treatment of Sjogren's syndrome, including administering an effective amount of the compound represented by the formula (I) or a pharmaceutically acceptable salt thereof, to a subject in need thereof. |
| 主权项 |
1. A method for the treatment of Sjogren's syndrome, comprising administering an effective amount of a compound represented by the formula (I): wherein n is an integer of 1-3; R is each independently an aliphatic group, haloalkyl, aryl, arylalkyl, alkoxy, cycloalkoxy, haloalkoxy, aryloxy, arylalkoxy, alkylthio, a halogen atom, nitro, cyano, hydroxy, NR1CO2R2, C(O)N(R1)2, C(O)R2, CO2R2, OC(O)N(R1)2, OC(O)R2, N(R1)2 or NR1C(O)R2; or two adjacent R groups form, together with an atom bonded thereto, a condensed, saturated, unsaturated, or partially unsaturated 5- to 7-membered ring having 0, 1 or 2 hetero atoms selected from N, O and S; R1 is each independently a hydrogen atom or an aliphatic group; and R2 is an aliphatic group, or a pharmaceutically acceptable salt thereof, to a subject in need thereof. |
