5-[(1-ARYL-3R-1H- PYRAZOL -4-YL)METHYLENE]-2-THIOXO-1,3-THIAZOLIDIN-4-ONES EXHIBITING HYPOGLYCEMIC ACTIVITY

摘要

5-[(1-Aryl-3R-1H- pyrazol -4-yl)methylene]-2-thioxo-1,3-thiazolidin-4-ones of general formula:,wherein Ar=Ph, R=4-ClCH(I); Ar=Ph, R=3-MeOCH(II); Ar=Ph, R=4-thienyl -2 (III); Ar=Ph, R=4-EtOC(O) (IV); Ar=4-BrCH, R=4-EtOC(O) (V); Ar=4-MeCH, R=4-EtOC(O) (VI),exhibiting hypoglycemic activity.