发明名称 Organic compounds
摘要 A depot formulation comprising iloperidone and a biodegradable, biocompatible polymer. Preferably, the polymer is a star polymer.
申请公布号 US8815293(B2) 申请公布日期 2014.08.26
申请号 US201012784251 申请日期 2010.05.20
申请人 Novartis AG 发明人 Ahlheim Markus;Loeffler Rolf
分类号 A61K9/14;A61K31/454 主分类号 A61K9/14
代理机构 Hoffman Warnick LLC 代理人 Hoffman Warnick LLC ;Holmes Drew
主权项 1. An intramuscular or subcutaneous depot formulation comprising iloperidone and a biodegradable, biocompatible polymer, wherein the depot formulation is in the form of microparticles, wherein the formulation includes from 50 percent to 90 percent iloperidone by weight, wherein the formulation, following a single intramuscular or subcutaneous injection, provides an effective treatment amount of iloperidone over a period of over about 2 weeks and up to about 6 weeks, and wherein the polymer is a polylactide-co-glycolide.
地址 Basel CH